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The Duex5 has the following features:
5 additional TMC2660 stepper motor drivers with stall notification.
5 additional extruder heater outputs.
5 servo outputs with 5V power and 5V signal levels, sharing control channels with the heaters, so you can use unused heater channels to drive servos.
5 additional endstop inputs with indicator LEDs and 3.3V/5V voltage selection. These are also usable as outputs.
6 additional controlled fan outputs, also usable for driving LEDs etc. The output voltage may be switched between 5V, 12V and VIN.
4 uncommitted general purpose I/O pins.
12V switching regulator, for generating a 12V supply for fans, LEDs etc. when the VIN power is higher than 12V.
5 additional thermistor inputs.
Support for 2 more thermocouple or PT100 daughter boards, supporting up to 4 more sensors.
Optional 5V external power input for powering servos, fans etc.